It is common for the following error to fill the application logs.
"EPiServer.Global : Unhandled exception in ASP.NET System.Web.HttpException (0x80004005): The file '/link/43F936C99B234EA397B261C538AD07C9.aspx' does not exist.
The error indicates a failure to load the root page of the site. When someone browses to your site it will first check if the browsed URL matches a binding from the manage websites screen. If the URL matches nothing, then the root page is loaded. If the root page does not have a template, then this error occurs.
Check the manage websites section(in the CMS admin) and confirm that the proper bindings exist for the site. To be thorough add a wildcard binding.
If that fails check if tblWorkContent has multiples of the same root page.